2024
Scientific Publication

Effectiveness of pyriproxyfen-pyrethroid and chlorfenapyr-pyrethroid long-lasting insecticidal nets (LLINs) compared with pyrethroid-only LLINs for malaria control in the third year post-distribution: a secondary analysis of a cluster-randomised controlled trial in Benin

Authors: Manfred Accrombessi, PhDa,* manfred.accrombessi@lshtm.ac.uk ∙ Jackie Cook, PhDb,* ∙ Edouard Dangbenon, MScc ∙ Arthur Sovi, PhDa,d ∙ Boulais Yovogan, MScc ∙ Landry Assongba, MScc ∙ Constantin J Adoha, MScc ∙ Bruno Akinro, MScc ∙ Cyriaque Affoukou, MDe ∙ Germain Gil Padonou, PhDc ∙ Immo Kleinschmidt, PhDb,f,g ∙ Louisa A Messenger, PhDa,h,i ∙ Mark Rowland, PhDa ∙ Corine Ngufor, PhDa ∙ Martin C Akogbeto, PhDc,† ∙ Natacha Protopopoff, PhDa,†

Abstract

Malaria continues to kill approximately 650 000 people each year. There is evidence that some second-generation insecticide-treated nets, which combine insecticide formulations with different modes of action, are protective against malaria while the nets are new; however, evidence for their impact over 3 years is scarce. In this study, we report the third-year results of a cluster-randomised controlled trial assessing the long-term effectiveness of dual-active ingredient long-lasting insecticidal nets (LLINs).

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